STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_0066PFAM: tRNA/rRNA methyltransferase (SpoU). (231 aa)    
Predicted Functional Partners:
Msed_0065
TIGRFAM: putative methylase; PFAM: methyltransferase small.
     
 0.953
Msed_0063
PFAM: protein of unknown function DUF655.
 
     0.947
Msed_0064
PFAM: ribosomal RNA adenine methylase transferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
       0.942
rpl21e
PFAM: ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.
 
     0.867
Msed_0062
DNA-directed RNA polymerase, subunit F; PFAM: RNA polymerase Rpb4.
       0.851
rps3ae
PFAM: ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family.
       0.851
Msed_0068
PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase.
       0.835
Msed_0661
RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
 
  
 0.739
Msed_1877
TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; Prephenate dehydrogenase; NADP oxidoreductase, coenzyme F420-dependent; Shikimate/quinate 5-dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding.
 
  
 0.482
Msed_2256
PFAM: peptidylprolyl isomerase, FKBP-type.
 
     0.477
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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