Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
Msed_0147Biotin carboxylase; PFAM: Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein. (510 aa)    
Predicted Functional Partners:
Msed_0148
PFAM: biotin/lipoyl attachment domain-containing protein.
 
 0.999
Msed_1375
Acetyl-CoA/propionyl-CoA carboxylase; PFAM: carboxyl transferase.
 
 0.992
Msed_2010
TIGRFAM: biotin--acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase.
 
 0.965
Msed_0267
PFAM: AMP-dependent synthetase and ligase.
  
 0.938
Msed_1291
PFAM: AMP-dependent synthetase and ligase.
  
 0.938
Msed_1353
Acetyl-coenzyme A synthetase; TIGRFAM: acetate--CoA ligase; PFAM: AMP-dependent synthetase and ligase.
  
 0.938
Msed_1522
TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase.
    
 0.921
Msed_1399
PFAM: CoA-binding domain protein.
    
 0.915
Msed_0709
succinyl-CoA reductase (NADPH); Catalyzes the reduction of malonyl-CoA to malonate semialdehyde, a key step in the 3-hydroxypropanoate and the 3- hydroxypropanoate/4-hydroxybutyrate cycles. Belongs to the aspartate-semialdehyde dehydrogenase family.
    
 0.914
Msed_0639
methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
    
  0.906
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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