Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Msed_0229Transcriptional regulator, ArsR family; PFAM: regulatory protein, ArsR. (110 aa)    
Predicted Functional Partners:
Msed_0230
Small nuclear ribonucleoprotein, LSM family; PFAM: Like-Sm ribonucleoprotein, core; SMART: Like-Sm ribonucleoprotein, eukaryotic and archaea-type, core.
 
     0.763
Msed_0231
PFAM: S-adenosylmethionine synthetase (MAT).
       0.528
Msed_2035
PFAM: Sjogrens syndrome scleroderma autoantigen 1.
  
     0.510
Msed_2273
PFAM: protein of unknown function DUF75.
  
     0.506
Msed_1526
Phosphohydrolase (DHH superfamily)-like protein.
 
     0.495
Msed_1584
PFAM: Glycosyltransferase 28, C-terminal domain.
 
   
 0.455
Msed_0490
Heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein.
  
  
 0.444
Msed_0232
PFAM: protein of unknown function DUF460.
 
     0.419
Msed_0667
SMART: von Willebrand factor, type A.
  
    0.402
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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