STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Msed_0232PFAM: protein of unknown function DUF460. (602 aa)    
Predicted Functional Partners:
Msed_0233
PFAM: protein of unknown function RIO1.
 
     0.878
Msed_2273
PFAM: protein of unknown function DUF75.
  
     0.622
Msed_1725
PFAM: helix-turn-helix domain protein.
 
     0.573
Msed_1661
PFAM: protein of unknown function DUF75.
  
     0.572
Msed_0733
Transcriptional regulator containing an HTH domain fused to a Zn-ribbon-like protein.
  
     0.564
Msed_0234
Hypothetical protein.
       0.563
tfe
Transcription factor IIE (TFIIE), alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elo [...]
  
     0.561
Msed_0006
TIGRFAM: putative adenylyl cyclase CyaB; PFAM: adenylate cyclase.
  
     0.551
Msed_2035
PFAM: Sjogrens syndrome scleroderma autoantigen 1.
  
     0.551
Msed_1758
Pseudouridylate synthase-like protein.
  
     0.548
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.