Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_0233PFAM: protein of unknown function RIO1. (285 aa)    
Predicted Functional Partners:
Msed_0739
Nucleic acid-binding protein consists of a PIN domain and a Zn-ribbon module-like protein.
   
 0.996
Msed_0653
PFAM: KH, type 1, domain protein; SMART: KH domain protein.
  
 
 0.973
rps6e
PFAM: ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.
  
  0.967
Msed_0232
PFAM: protein of unknown function DUF460.
 
     0.964
rps15
PFAM: ribosomal protein S15; ribosomal S13S15-like.
  
 
 0.964
rps5
SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy.
 
 0.961
rps11
SSU ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family.
  
 0.960
rps3ae
PFAM: ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family.
  
 0.957
rps3
SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
   
 0.956
rps4
SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
 0.954
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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