STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_0236PFAM: sugar isomerase (SIS). (209 aa)    
Predicted Functional Partners:
Msed_0227
3-hexulose-6-phosphate synthase; PFAM: Orotidine 5'-phosphate decarboxylase.
 
 0.999
Msed_1856
TIGRFAM: bifunctional phosphoglucose/phosphomannose isomerase.
    
 0.917
Msed_2078
Bifunctional phosphoglucose/phosphomannose isomerase.
    
 0.917
fbp
Fructose-bisphosphate aldolase / D-fructose 1,6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
     
 0.915
Msed_1878
Transketolase subunit B; PFAM: Transketolase, central region; Transketolase domain protein.
    
  0.902
Msed_1879
PFAM: Transketolase domain protein.
    
  0.902
cysH
Phosphoadenylylsulfate reductase (thioredoxin); Appears to have a role in S metabolism; TIGRFAM: adenylylsulfate reductase, thioredoxin dependent; PFAM: phosphoadenosine phosphosulfate reductase.
     
 0.744
Msed_2287
TIGRFAM: ribose 5-phosphate isomerase; PFAM: Ribose 5-phosphate isomerase.
 
  
 0.634
Msed_0162
Hypothetical protein.
       0.541
Msed_1297
2-keto-3-deoxygalactonate kinase / 2-keto-3-deoxygluconate kinase; PFAM: PfkB domain protein.
 
  
 0.534
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.