Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Msed_0240PFAM: Nucleotidyl transferase. (251 aa)    
Predicted Functional Partners:
Msed_1802
PFAM: RNA binding S1 domain protein; translation initiation factor 2, alpha subunit.
   
 0.860
Msed_1851
dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
 
  
 0.859
Msed_1810
PFAM: UDP-glucose/GDP-mannose dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein.
 
  
 0.741
Msed_1850
TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain.
 
  
 0.740
Msed_0241
UDP-sulfoquinovose synthase; PFAM: NAD-dependent epimerase/dehydratase.
  
 
 0.728
Msed_0642
PFAM: protein synthesis factor, GTP-binding; elongation factor Tu domain protein; elongation factor Tu, domain 2 protein.
  
 0.706
Msed_2208
Selenocysteine-specific translation elongation factor-like protein.
  
 0.706
Msed_2243
Translation initiation factor 2 subunit gamma (aeIF-2g); PFAM: protein synthesis factor, GTP-binding.
  
 0.706
Msed_0237
PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase.
 
     0.702
Msed_1419
PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase.
 
     0.690
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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