STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_0245PFAM: MazG nucleotide pyrophosphohydrolase. (81 aa)    
Predicted Functional Partners:
tmcA
Protein of unknown function DUF699, ATPase putative; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
 
     0.949
Msed_0244
Hypothetical protein.
       0.942
hisE
PFAM: phosphoribosyl-ATP pyrophosphohydrolase.
     
 0.766
Msed_0243
Gamma-glutamyltransferase 2, Threonine peptidase, MEROPS family T03; PFAM: gamma-glutamyltranspeptidase.
       0.608
Msed_0006
TIGRFAM: putative adenylyl cyclase CyaB; PFAM: adenylate cyclase.
 
     0.541
hisF
Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
 
     0.516
Msed_0126
PFAM: triphosphoribosyl-dephospho-CoA protein.
  
     0.503
Msed_0631
TIGRFAM: dihydropteroate synthase-related protein.
  
    0.445
htpX
Heat shock protein, Metallo peptidase, MEROPS family M48B; PFAM: peptidase M48, Ste24p; Belongs to the peptidase M48B family.
       0.407
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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