Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_0260Metallopeptidase-like protein. (127 aa)    
Predicted Functional Partners:
Msed_0259
Hypothetical protein.
       0.608
Msed_0261
Hypothetical protein.
       0.588
Msed_0262
Hypothetical protein.
       0.588
Msed_0622
Zn-dependent hydrolase of the beta-lactamase fold-like protein.
  
   
 0.560
Msed_1085
Dehydrogenase (flavoprotein)-like protein.
 
     0.541
Msed_0258
PFAM: major facilitator superfamily MFS_1.
 
     0.527
Msed_0754
Hypothetical protein.
  
     0.521
Msed_0208
PFAM: protein of unknown function DUF1610.
  
     0.472
Msed_0687
PFAM: FAD dependent oxidoreductase.
 
     0.450
Msed_2111
PFAM: ParB domain protein nuclease.
  
     0.413
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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