STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Msed_02782-methylcitrate dehydratase; PFAM: MmgE/PrpD family protein. (428 aa)    
Predicted Functional Partners:
Msed_0279
2,3-dimethylmalate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
 
  
 0.996
Msed_1522
TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase.
 
 
 0.983
Msed_1467
Aconitase; TIGRFAM: aconitate hydratase 1; PFAM: aconitate hydratase domain protein.
  
 
 0.944
Msed_0281
TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase.
 
  
 0.942
Msed_0280
Putative signal-transduction protein with CBS domains; PFAM: CBS domain containing protein.
       0.753
Msed_1375
Acetyl-CoA/propionyl-CoA carboxylase; PFAM: carboxyl transferase.
  
    0.714
Msed_0276
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain.
  
  
 0.658
Msed_0415
PFAM: NADH:flavin oxidoreductase/NADH oxidase.
  
  
 0.639
Msed_0275
4-aminobutyrate aminotransferase apoenzyme; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.621
Msed_0277
Xanthine dehydrogenase, molybdenum binding subunit apoprotein; PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding.
  
    0.571
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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