STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_0290PFAM: cytochrome c oxidase, subunit I; Belongs to the heme-copper respiratory oxidase family. (550 aa)    
Predicted Functional Partners:
Msed_0291
PFAM: Cytochrome b/b6, N-terminal domain.
 
 0.998
Msed_0289
PFAM: cytochrome c oxidase, subunit II.
  
 0.997
Msed_0320
PFAM: cytochrome c oxidase, subunit II.
 
 0.997
foxB
Cytochrome c oxidase, subunit II; This soxH-like sequence appears to have a function related to Fe(II) oxidation; PFAM: cytochrome c oxidase, subunit II.
 
 0.994
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
 
 0.993
Msed_0324
PFAM: cytochrome c oxidase, subunit III; cytochrome c oxidase, subunit I; Belongs to the heme-copper respiratory oxidase family.
 
  
0.936
Msed_0321
PFAM: Cytochrome b/b6, N-terminal domain.
 
 
 0.932
Msed_1898
PFAM: respiratory-chain NADH dehydrogenase, subunit 1.
  
 
 0.922
soxN
Cytochrome b/b6, N-terminal domain; Appears to have a function related to Fe(II) oxidation; PFAM: Cytochrome b/b6, N-terminal domain.
 
 
 0.919
Msed_1903
PFAM: NADH/Ubiquinone/plastoquinone (complex I).
  
 
 0.918
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.