STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_0295PFAM: protein of unknown function DUF224, cysteine-rich region domain protein. (399 aa)    
Predicted Functional Partners:
Msed_0296
PFAM: Rubrerythrin.
 
   
 0.981
Msed_1177
PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase.
 
 
 0.961
Msed_0294
Hypothetical protein.
 
     0.959
Msed_0436
D-lactate dehydrogenase; PFAM: FAD linked oxidase domain protein.
 
  
 0.920
egsA
3-dehydroquinate synthase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
    
  0.900
Msed_1118
D-lactate dehydrogenase; PFAM: FAD linked oxidase domain protein.
 
  
 0.884
Msed_1466
PFAM: protein of unknown function DUF162.
 
 
 0.843
Msed_0553
PFAM: FAD linked oxidase domain protein.
  
 0.607
Msed_1041
PFAM: L-lactate permease.
 
  
 0.524
gap
TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II; PFAM: glyceraldehyde 3-phosphate dehydrogenase; dihydrodipicolinate reductase.
 
  
 0.522
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.