STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_0322PFAM: Rieske [2Fe-2S] domain protein. (272 aa)    
Predicted Functional Partners:
Msed_0321
PFAM: Cytochrome b/b6, N-terminal domain.
 
 0.996
Msed_0291
PFAM: Cytochrome b/b6, N-terminal domain.
 
 0.964
soxN
Cytochrome b/b6, N-terminal domain; Appears to have a function related to Fe(II) oxidation; PFAM: Cytochrome b/b6, N-terminal domain.
 
 0.961
Msed_0320
PFAM: cytochrome c oxidase, subunit II.
 
 
 0.960
Msed_1899
TIGRFAM: NADH-quinone oxidoreductase, chain I; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein.
  
 
 0.915
Msed_1897
PFAM: NADH-ubiquinone oxidoreductase, chain 49kDa; Belongs to the complex I 49 kDa subunit family.
  
 
 0.913
Msed_0676
TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein.
  
 
 0.911
Msed_1896
TIGRFAM: NADH (or F420H2) dehydrogenase, subunit C; PFAM: NADH dehydrogenase (ubiquinone), 30 kDa subunit.
  
 
 0.911
Msed_2012
TIGRFAM: NADH-quinone oxidoreductase, B subunit; PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit; Belongs to the complex I 20 kDa subunit family.
  
 
 0.885
Msed_0677
TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.852
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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