Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_0334PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein. (87 aa)    
Predicted Functional Partners:
Msed_0331
PFAM: electron transfer flavoprotein beta-subunit.
 
 0.989
Msed_0333
FAD dependent oxidoreductase; PFAM: monooxygenase, FAD-binding; HI0933 family protein; FAD dependent oxidoreductase.
 
 
 0.989
Msed_0332
PFAM: electron transfer flavoprotein beta-subunit; electron transfer flavoprotein, alpha subunit.
 
 0.987
Msed_1248
PFAM: electron transfer flavoprotein beta-subunit; electron transfer flavoprotein, alpha subunit.
 
 0.950
Msed_1249
FAD dependent oxidoreductase; PFAM: monooxygenase, FAD-binding; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
 
 
 0.882
Msed_1467
Aconitase; TIGRFAM: aconitate hydratase 1; PFAM: aconitate hydratase domain protein.
   
 
 0.748
Msed_0336
PFAM: Enoyl-CoA hydratase/isomerase.
  
 
 0.732
Msed_0206
PFAM: tRNA pseudouridine synthase D, TruD.
    
   0.676
Msed_0681
2,3-di-O-geranylgeranylglyceryl phosphate reductase; TIGRFAM: geranylgeranyl reductase; PFAM: FAD dependent oxidoreductase.
 
 
 0.634
Msed_0335
PFAM: von Willebrand factor, type A.
       0.610
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
Server load: medium (54%) [HD]