STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_0350PFAM: ABC transporter related; SMART: AAA ATPase. (273 aa)    
Predicted Functional Partners:
Msed_0349
Hypothetical protein.
  
  
 0.965
Msed_0520
Hypothetical protein.
  
 
 0.715
Msed_0251
PFAM: ABC-2 type transporter.
 
  
 0.666
Msed_0567
PFAM: ABC-2 type transporter.
 
  
 0.563
Msed_0870
PFAM: ABC-2 type transporter.
 
  
 0.548
Msed_1180
Carbohydrate ABC transporter ATP-binding protein, CUT1 family; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; TC 3.A.1.1.-.
     0.487
Msed_1530
PFAM: ABC transporter related; SMART: AAA ATPase.
  
0.466
Msed_0868
PFAM: transcriptional regulator PadR family protein.
 
    0.463
rpl14
LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
 
    0.461
fusA
Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...]
 
  
 0.448
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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