STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Msed_0386Propanoyl-CoA C-acyltransferase; PFAM: Thiolase. (387 aa)    
Predicted Functional Partners:
Msed_1646
TIGRFAM: putative hydroxymethylglutaryl-CoA synthase; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal domain protein; Belongs to the thiolase-like superfamily. UPF0219 family.
 
 0.996
Msed_0389
PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding.
  
 0.986
Msed_0387
PFAM: protein of unknown function DUF35.
 
 
 0.980
Msed_1218
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain.
 
 0.976
Msed_0281
TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase.
  
 0.959
Msed_1522
TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase.
  
 0.959
Msed_1648
PFAM: protein of unknown function DUF35.
 
 
 0.950
Msed_0399
PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.944
Msed_1423
PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding.
  
 0.944
Msed_1399
PFAM: CoA-binding domain protein.
  
 
  0.937
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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