STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Msed_0407PFAM: General substrate transporter; major facilitator superfamily MFS_1. (427 aa)    
Predicted Functional Partners:
Msed_0408
Amino acid/polyamine/organocation transporter, APC superfamily; PFAM: Spore germination protein; amino acid permease-associated region; TC 2.A.3.
 
   0.711
Msed_0255
PFAM: General substrate transporter; major facilitator superfamily MFS_1.
  
     0.523
Msed_0409
Amino acid/polyamine/organocation transporter, APC superfamily; PFAM: amino acid permease-associated region; TC 2.A.3.
  
   0.459
Msed_0406
AMP-dependent synthetase and ligase; Involved in the 3-hydroxypropionate/4-hydroxybutyrate cycle which incorporates carbon dioxide into cellular carbon. Catalyzes the ligation of coenzyme A (CoA) to 4-hydroxybutyrate (4HB). It can also use butyrate, valerate, propionate, acetate and 3-hydroxybutyrate (3HB) as substrates; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.448
Msed_0405
Ala-tRNA(Pro) hydrolase; Related to alanyl-tRNA synthetase HxxxH domain-like protein.
       0.440
Msed_0860
PFAM: General substrate transporter; major facilitator superfamily MFS_1.
  
     0.416
Msed_2162
PFAM: major facilitator superfamily MFS_1.
  
     0.414
Msed_0457
PFAM: General substrate transporter; major facilitator superfamily MFS_1.
  
     0.412
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.