Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Msed_0428PFAM: NADPH-dependent FMN reductase; flavodoxin/nitric oxide synthase. (197 aa)    
Predicted Functional Partners:
Msed_1237
Methyltransferase type 11; PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11.
   
 
  0.903
Msed_1305
PFAM: high-affinity nickel-transporter; Belongs to the NiCoT transporter (TC 2.A.52) family.
      
 0.764
Msed_0430
PFAM: isochorismatase hydrolase.
  
  
 0.588
Msed_0429
Hypothetical protein.
       0.512
Msed_0237
PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase.
  
    0.499
Msed_0452
PFAM: aldo/keto reductase.
  
  
 0.455
Msed_2051
Phospholipid-binding protein, PBP family; PFAM: PEBP family protein.
  
  
 0.446
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
  
  
 0.427
Msed_0517
Uncharacterized flavoprotein-like protein.
 
  
 0.427
Msed_1878
Transketolase subunit B; PFAM: Transketolase, central region; Transketolase domain protein.
  
    0.420
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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