STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_0430PFAM: isochorismatase hydrolase. (184 aa)    
Predicted Functional Partners:
Msed_1527
PFAM: isochorismatase hydrolase.
  
     0.607
Msed_0428
PFAM: NADPH-dependent FMN reductase; flavodoxin/nitric oxide synthase.
  
  
 0.588
Msed_0429
Hypothetical protein.
       0.543
Msed_0431
Pyruvate, water dikinase; PFAM: pyruvate phosphate dikinase, PEP/pyruvate-binding.
       0.525
Msed_1292
PFAM: SMP-30/Gluconolaconase/LRE domain protein.
 
    0.504
Msed_2058
Hydrolase or acyltransferase (alpha/beta hydrolase superfamily)-like protein.
 
 
 0.453
Msed_0639
methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
 
  
 0.426
Msed_0452
PFAM: aldo/keto reductase.
  
    0.418
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
  
    0.417
Msed_1623
PFAM: Quinolinate phosphoribosyl transferase.
  
  
 0.408
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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