STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Msed_0468Putative signal-transduction protein with CBS domains; PFAM: CBS domain containing protein; 4Fe-4S ferredoxin, iron-sulfur binding domain protein. (326 aa)    
Predicted Functional Partners:
Msed_0469
Hypothetical protein.
 
 
 0.872
Msed_0677
TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.793
Msed_1114
TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein.
  
 
 0.793
Msed_1399
PFAM: CoA-binding domain protein.
   
 
 0.785
rpl6
LSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
 
   0.748
Msed_0331
PFAM: electron transfer flavoprotein beta-subunit.
   
 
 0.730
Msed_0532
Putative signal-transduction protein with CBS domains; TIGRFAM: ribosomal subunit interface protein; PFAM: CBS domain containing protein.
 
    0.728
Msed_1116
Fumarase alpha subunit; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region.
     
 0.719
Msed_1596
PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase.
  
  
 0.712
rps2
PFAM: ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
 
   0.653
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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