STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_0487PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (396 aa)    
Predicted Functional Partners:
Msed_0882
Assimilatory nitrate reductase (ferredoxin) precursor; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region.
   
 0.887
Msed_1885
PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein.
  
  
 0.847
Msed_1457
TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region.
   
 0.659
Msed_0488
PFAM: HEPN domain protein.
       0.648
Msed_0489
PFAM: DNA polymerase, beta domain protein region.
       0.648
Msed_0880
Nitrite and sulphite reductase 4Fe-4S region; PFAM: nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region.
 
 0.608
Msed_2009
Pyridine nucleotide-disulfide oxidoreductase dimerization region; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
 
 0.574
Msed_0513
PFAM: beta-lactamase domain protein.
 
 
 0.535
Msed_0486
Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein.
 
     0.507
Msed_0222
PFAM: FAD dependent oxidoreductase.
  
 
 0.477
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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