STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
cbsACbsA; Appears to have a function related to Fe(II) oxidation. (474 aa)    
Predicted Functional Partners:
cbsB
CbsB; Appears to have a function related to Fe(II) oxidation.
     
 0.972
soxL
Rieske (2Fe-2S) domain protein; Appears to have a function related to Fe(II) oxidation; PFAM: Rieske [2Fe-2S] domain protein.
     
 0.608
Msed_0505
TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; plasma-membrane proton-efflux P-type ATPase; PFAM: cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein.
       0.568
Msed_0291
PFAM: Cytochrome b/b6, N-terminal domain.
     
 0.540
Msed_0321
PFAM: Cytochrome b/b6, N-terminal domain.
     
 0.532
Msed_0506
Hypothetical protein.
       0.508
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
      
 0.504
soxN
Cytochrome b/b6, N-terminal domain; Appears to have a function related to Fe(II) oxidation; PFAM: Cytochrome b/b6, N-terminal domain.
     
 0.472
foxA
Cytochrome c oxidase, subunit I; This soxB-like sequence appears to have a role in Fe(II) oxidation; PFAM: cytochrome c oxidase, subunit I.
      
 0.405
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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