STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_0531PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase. (240 aa)    
Predicted Functional Partners:
Msed_2074
Glutamate dehydrogenase (NAD/NADP); PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.950
Msed_0532
Putative signal-transduction protein with CBS domains; TIGRFAM: ribosomal subunit interface protein; PFAM: CBS domain containing protein.
       0.942
Msed_1684
L-aspartate aminotransferase apoenzyme; PFAM: aminotransferase, class I and II.
  
 
 0.938
Msed_0703
TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase.
  
 
  0.884
Msed_0455
PFAM: Lactate/malate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.861
pckG
Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
  
 
  0.821
Msed_0281
TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase.
  
 
  0.812
Msed_1522
TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase.
  
 
  0.812
Msed_0524
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding.
  
 
  0.810
Msed_0525
PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
  
 
  0.803
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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