STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
Msed_0558Sulfide dehydrogenase (flavocytochrome), flavoprotein subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (358 aa)    
Predicted Functional Partners:
cysI
Sulfite reductase (NADPH) beta subunit; Appears to have a role in S metabolism; PFAM: nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region.
  
 0.922
Msed_0673
Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes.
  
 
 0.916
Msed_2080
NADPH:sulfur oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region.
    
  0.903
Msed_0967
PFAM: selenium-binding protein.
     
  0.900
cysN
Sulfate adenylyltransferase; Appears to have a role in S metabolism; PFAM: ATP-sulfurylase.
     
 0.735
Msed_0559
GTP:adenosylcobinamide-phosphate guanylyltransferase-like protein.
       0.561
Msed_0560
PFAM: protein of unknown function DUF1614.
       0.543
Msed_0222
PFAM: FAD dependent oxidoreductase.
  
 
 0.477
Msed_0369
PFAM: beta-lactamase domain protein.
   
 0.477
Msed_0513
PFAM: beta-lactamase domain protein.
   
 0.477
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.