STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_0575PFAM: peptidase M1, membrane alanine aminopeptidase. (778 aa)    
Predicted Functional Partners:
fusA
Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...]
 
 
 0.758
Msed_1877
TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; Prephenate dehydrogenase; NADP oxidoreductase, coenzyme F420-dependent; Shikimate/quinate 5-dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding.
     
 0.602
Msed_0703
TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase.
    
 0.572
Msed_0863
PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase.
 
 
 0.572
Msed_0531
PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase.
 
 
 0.563
Msed_0833
PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase.
 
 
 0.557
Msed_1791
PFAM: protein of unknown function, ATP binding.
 
 
 0.551
Msed_1797
PFAM: protein kinase; SMART: serine/threonine protein kinase.
 
 
 0.548
Msed_0329
PFAM: protein kinase; SMART: serine/threonine protein kinase.
 
 
 0.540
Msed_2110
DNA-(apurinic or apyrimidinic site) lyase; PFAM: HhH-GPD family protein; SMART: iron-sulfur cluster loop.
     
 0.528
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.