node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Msed_0653 | Msed_1722 | Msed_0653 | Msed_1722 | PFAM: KH, type 1, domain protein; SMART: KH domain protein. | rRNA biogenesis protein Nop56/Nop58; PFAM: Pre-mRNA processing ribonucleoprotein, binding region; NOSIC. | 0.998 |
Msed_0653 | csl4 | Msed_0653 | Msed_1863 | PFAM: KH, type 1, domain protein; SMART: KH domain protein. | RNA binding S1 domain protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | 0.982 |
Msed_0653 | nep1 | Msed_0653 | Msed_0747 | PFAM: KH, type 1, domain protein; SMART: KH domain protein. | Suppressor Mra1; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. | 0.999 |
Msed_0653 | rps11 | Msed_0653 | Msed_2146 | PFAM: KH, type 1, domain protein; SMART: KH domain protein. | SSU ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. | 0.999 |
Msed_0653 | rps12 | Msed_0653 | Msed_0038 | PFAM: KH, type 1, domain protein; SMART: KH domain protein. | SSU ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. | 0.982 |
Msed_0653 | rps4 | Msed_0653 | Msed_2147 | PFAM: KH, type 1, domain protein; SMART: KH domain protein. | SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.998 |
Msed_0653 | rps6e | Msed_0653 | Msed_2244 | PFAM: KH, type 1, domain protein; SMART: KH domain protein. | PFAM: ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. | 0.997 |
Msed_0653 | rrp4 | Msed_0653 | Msed_0076 | PFAM: KH, type 1, domain protein; SMART: KH domain protein. | Ribosomal RNA-processing protein RRP4; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. | 0.966 |
Msed_0653 | rrp42 | Msed_0653 | Msed_0078 | PFAM: KH, type 1, domain protein; SMART: KH domain protein. | Ribosomal RNA-processing protein RRP42; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. | 0.962 |
Msed_0653 | rtcA | Msed_0653 | Msed_0600 | PFAM: KH, type 1, domain protein; SMART: KH domain protein. | RNA-3'-phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. | 0.975 |
Msed_1722 | Msed_0653 | Msed_1722 | Msed_0653 | rRNA biogenesis protein Nop56/Nop58; PFAM: Pre-mRNA processing ribonucleoprotein, binding region; NOSIC. | PFAM: KH, type 1, domain protein; SMART: KH domain protein. | 0.998 |
Msed_1722 | csl4 | Msed_1722 | Msed_1863 | rRNA biogenesis protein Nop56/Nop58; PFAM: Pre-mRNA processing ribonucleoprotein, binding region; NOSIC. | RNA binding S1 domain protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | 0.970 |
Msed_1722 | nep1 | Msed_1722 | Msed_0747 | rRNA biogenesis protein Nop56/Nop58; PFAM: Pre-mRNA processing ribonucleoprotein, binding region; NOSIC. | Suppressor Mra1; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. | 0.999 |
Msed_1722 | rps11 | Msed_1722 | Msed_2146 | rRNA biogenesis protein Nop56/Nop58; PFAM: Pre-mRNA processing ribonucleoprotein, binding region; NOSIC. | SSU ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. | 0.988 |
Msed_1722 | rps12 | Msed_1722 | Msed_0038 | rRNA biogenesis protein Nop56/Nop58; PFAM: Pre-mRNA processing ribonucleoprotein, binding region; NOSIC. | SSU ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. | 0.979 |
Msed_1722 | rps4 | Msed_1722 | Msed_2147 | rRNA biogenesis protein Nop56/Nop58; PFAM: Pre-mRNA processing ribonucleoprotein, binding region; NOSIC. | SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.992 |
Msed_1722 | rps6e | Msed_1722 | Msed_2244 | rRNA biogenesis protein Nop56/Nop58; PFAM: Pre-mRNA processing ribonucleoprotein, binding region; NOSIC. | PFAM: ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. | 0.996 |
Msed_1722 | rrp4 | Msed_1722 | Msed_0076 | rRNA biogenesis protein Nop56/Nop58; PFAM: Pre-mRNA processing ribonucleoprotein, binding region; NOSIC. | Ribosomal RNA-processing protein RRP4; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. | 0.952 |
Msed_1722 | rrp42 | Msed_1722 | Msed_0078 | rRNA biogenesis protein Nop56/Nop58; PFAM: Pre-mRNA processing ribonucleoprotein, binding region; NOSIC. | Ribosomal RNA-processing protein RRP42; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. | 0.958 |
Msed_1722 | rtcA | Msed_1722 | Msed_0600 | rRNA biogenesis protein Nop56/Nop58; PFAM: Pre-mRNA processing ribonucleoprotein, binding region; NOSIC. | RNA-3'-phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. | 0.994 |