Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
Msed_0637PFAM: phosphoribosyltransferase. (179 aa)    
Predicted Functional Partners:
Msed_0636
PFAM: type I phosphodiesterase/nucleotide pyrophosphatase.
       0.801
Msed_2134
PFAM: glycosyl transferase, family 4.
     
 0.765
rps17e
SSU ribosomal protein S17E; Belongs to the eukaryotic ribosomal protein eS17 family.
  
    0.564
Msed_0635
PFAM: amine oxidase; FAD dependent oxidoreductase.
       0.556
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
  
 0.497
Msed_0634
PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; Belongs to the AAA ATPase family.
       0.477
Msed_0008
Hypothetical protein.
   
    0.423
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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