STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_0650PFAM: type II secretion system protein E. (572 aa)    
Predicted Functional Partners:
Msed_0651
PFAM: type II secretion system protein.
 
  
 0.903
Msed_1324
Flagella assembly protein J-like protein.
 
  
 0.828
Msed_1326
ATPase involved in biogenesis of flagella-like protein.
 
  
 0.774
Msed_1328
Hypothetical protein.
  
  
 0.741
Msed_1198
Type II secretion system protein; This flaJ-like permease was upregulated on Fe(II) oxidation; PFAM: type II secretion system protein.
  
  
 0.618
Msed_2105
Hypothetical protein.
  
  
 0.595
Msed_1327
Hypothetical protein.
  
  
 0.553
Msed_1330
Flagellin-like protein; Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.
  
  
 0.552
rpl18e
PFAM: ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL18 family.
  
     0.444
dnaG
TOPRIM domain protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
 
   
 0.435
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.