Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
Msed_0691PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (279 aa)    
Predicted Functional Partners:
uppS
Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
 
 
 0.986
Msed_1075
PFAM: Squalene/phytoene synthase.
  
 0.952
mtnP
Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
       0.931
Msed_0690
Hypothetical protein.
       0.931
Msed_2135
Geranylgeranyl-diphosphate synthase / farnesyl-diphosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
  
  
0.924
Msed_1036
PFAM: UbiA prenyltransferase.
 
  
 0.875
Msed_0692
SSU ribosomal protein S6P modification protein; TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp.
       0.867
Msed_2096
TIGRFAM: 4-hydroxybenzoate polyprenyltransferase, putative; PFAM: UbiA prenyltransferase.
  
 
 0.854
Msed_0415
PFAM: NADH:flavin oxidoreductase/NADH oxidase.
  
  
 0.773
Msed_0687
PFAM: FAD dependent oxidoreductase.
  
 
 0.744
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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