Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
Msed_0700PFAM: transcriptional coactivator/pterin dehydratase. (96 aa)    
Predicted Functional Partners:
Msed_1072
PFAM: Alpha/beta hydrolase fold-3 domain protein.
  
 
 0.509
moaC
GTP cyclohydrolase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
  
  
 0.487
Msed_1683
TIGRFAM: valyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.473
Msed_1403
TIGRFAM: putative endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP.
  
    0.464
moaA
GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
  
  
 0.463
Msed_0010
PFAM: histidine triad (HIT) protein.
  
   0.452
Msed_0726
PFAM: histidine triad (HIT) protein.
  
   0.452
Msed_1358
5-carboxymethyl-2-hydroxymuconate Delta-isomerase; PFAM: fumarylacetoacetate (FAA) hydrolase.
  
  
 0.417
Msed_1777
PFAM: fumarylacetoacetate (FAA) hydrolase.
  
  
 0.417
Msed_0911
Alpha-glucosidase; PFAM: glycoside hydrolase, family 31; Belongs to the glycosyl hydrolase 31 family.
    
   0.414
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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