STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_0733Transcriptional regulator containing an HTH domain fused to a Zn-ribbon-like protein. (91 aa)    
Predicted Functional Partners:
Msed_0732
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase.
       0.942
Msed_0735
PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Belongs to the UPF0284 family.
       0.929
Msed_0731
PFAM: methyltransferase small.
       0.796
Msed_0734
dTDP-4-dehydrorhamnose reductase; PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase.
       0.781
Msed_0736
Hypothetical protein.
       0.676
Msed_0232
PFAM: protein of unknown function DUF460.
  
     0.564
Msed_1758
Pseudouridylate synthase-like protein.
 
     0.544
rpl21e
PFAM: ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.
 
     0.494
Msed_1261
TIGRFAM: peptidase S26B, signal peptidase; PFAM: peptidase S24, S26A and S26B.
  
     0.460
gatE
glutamyl-tRNA(Gln) amidotransferase subunit E; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
       0.453
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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