STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prf1Peptide chain release factor subunit 1 (aeRF-1); Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (338 aa)    
Predicted Functional Partners:
Msed_2258
ABC transporter related protein; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; ABC transporter related; Possible metal-binding region in RNase L inhibitor, RLI; SMART: AAA ATPase.
  
 
 0.999
tuf
Translation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
  
 0.956
rpl15e
PFAM: ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family.
 
 0.954
rps15
PFAM: ribosomal protein S15; ribosomal S13S15-like.
 
 0.912
rps3ae
PFAM: ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family.
  
  0.909
rpl30
PFAM: ribosomal protein L30.
  
 0.909
rps4e
PFAM: RNA-binding S4 domain protein; ribosomal protein S4E-like; ribosomal protein S4E, central; Belongs to the eukaryotic ribosomal protein eS4 family.
  
  0.902
Msed_0065
TIGRFAM: putative methylase; PFAM: methyltransferase small.
   
 0.899
Msed_1802
PFAM: RNA binding S1 domain protein; translation initiation factor 2, alpha subunit.
  
 
 0.898
rps17
SSU ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
  
  0.897
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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