STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_0750PFAM: phosphoribosyltransferase. (207 aa)    
Predicted Functional Partners:
mtnP
Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
  
  
 0.882
Msed_2134
PFAM: glycosyl transferase, family 4.
     
 0.765
Msed_0692
SSU ribosomal protein S6P modification protein; TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp.
       0.563
Msed_0691
PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
  
    0.539
Msed_0690
Hypothetical protein.
       0.527
Msed_0751
Hypothetical protein.
       0.494
Msed_0868
PFAM: transcriptional regulator PadR family protein.
      
 0.484
Msed_0958
Protein of unknown function DUF650, N-terminal domain; Involved in DNA damage repair.
 
     0.459
Msed_0008
Hypothetical protein.
   
    0.423
Msed_2293
Transcriptional regulator, XRE family; PFAM: CBS domain containing protein; helix-turn-helix domain protein.
  
     0.410
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.