Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Msed_0772PFAM: metallophosphoesterase. (326 aa)    
Predicted Functional Partners:
Msed_2033
Hypothetical protein.
 
     0.788
Msed_0873
Hypothetical protein.
  
     0.749
Msed_0391
Amino acid/polyamine/organocation transporter, APC superfamily; TC 2.A.3.
 
     0.747
Msed_1503
Amino acid/polyamine/organocation transporter, APC superfamily; PFAM: amino acid permease-associated region; TC 2.A.3.
  
     0.724
Msed_1269
Amino acid/polyamine/organocation transporter, APC superfamily; PFAM: amino acid permease-associated region; TC 2.A.3.
  
     0.701
Msed_0773
PFAM: Phosphoglycerate mutase.
       0.483
Msed_0771
Putative signal-transduction protein with CBS domains; PFAM: CBS domain containing protein.
       0.461
Msed_0770
Hypothetical protein.
       0.410
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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