Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_0924PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit. (322 aa)    
Predicted Functional Partners:
Msed_0923
PFAM: nickel-dependent hydrogenase, large subunit.
 
 0.999
Msed_0920
Coenzyme F420-reducing hydrogenase alpha subunit-like protein.
 
 0.997
Msed_0945
Ni Fe-hydrogenase I large subunit-like protein.
 
 0.996
Msed_0944
PFAM: Nickel-iron dehydrogenase small subunit, N-terminal domain protein.
  
  
 
0.923
Msed_0921
Hypothetical protein.
       0.775
Msed_0922
Hypothetical protein.
       0.773
Msed_0916
Hydrogenase 2 maturation peptidase, Aspartic peptidase, MEROPS family A31; TIGRFAM: hydrogenase maturation protease; PFAM: peptidase M52, hydrogen uptake protein.
 
  
 0.709
Msed_0925
Hypothetical protein.
   
   0.661
Msed_0930
PFAM: hydrogenase formation HypD protein.
 
  
 0.539
Msed_0915
TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: acylphosphatase; SUA5/yciO/yrdC, N-terminal domain; zinc finger, HypF domain protein.
 
 
 
 0.531
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.