Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Msed_0930PFAM: hydrogenase formation HypD protein. (375 aa)    
Predicted Functional Partners:
Msed_0933
TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein.
 
 
 0.997
Msed_0931
TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC).
 
 
 0.990
Msed_0915
TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: acylphosphatase; SUA5/yciO/yrdC, N-terminal domain; zinc finger, HypF domain protein.
 
  
 0.963
Msed_0955
PFAM: AIR synthase related protein domain protein.
 
 
 0.955
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
  
  
 0.923
Msed_0917
PFAM: hydrogenase expression/formation protein (HUPF/HYPC).
  
 
 0.914
Msed_0918
Hypothetical protein.
  
 
 0.914
hypA
Hydrogenase expression/synthesis, HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
  
  
 0.835
Msed_0929
PFAM: class II aldolase/adducin family protein.
       0.795
Msed_1902
NADH dehydrogenase (quinone); PFAM: NADH/Ubiquinone/plastoquinone (complex I).
     
 0.785
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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