STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cysISulfite reductase (NADPH) beta subunit; Appears to have a role in S metabolism; PFAM: nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region. (599 aa)    
Predicted Functional Partners:
cysH
Phosphoadenylylsulfate reductase (thioredoxin); Appears to have a role in S metabolism; TIGRFAM: adenylylsulfate reductase, thioredoxin dependent; PFAM: phosphoadenosine phosphosulfate reductase.
 
 
 0.998
cysG
Appears to have a role in S metabolism; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase.
 
  
 0.974
cysN
Sulfate adenylyltransferase; Appears to have a role in S metabolism; PFAM: ATP-sulfurylase.
 
  
 0.959
Msed_0673
Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes.
  
 
 0.947
Msed_0356
PFAM: Rhodanese domain protein.
    
 0.935
Msed_1210
PFAM: Rhodanese domain protein.
    
 0.935
Msed_2059
Sulfide-quinone oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 0.932
Msed_0353
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 0.928
Msed_0558
Sulfide dehydrogenase (flavocytochrome), flavoprotein subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 0.922
Msed_1039
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 0.922
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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