Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Msed_0994PFAM: flavin reductase domain protein, FMN-binding. (146 aa)    
Predicted Functional Partners:
Msed_0645
Molybdopterin synthase subunit MoaD / molybdopterin synthase subunit MoaE; TIGRFAM: MoaD family protein; PFAM: molybdopterin biosynthesis MoaE protein; thiamineS protein.
 
     0.781
Msed_0996
4-hydroxyphenylacetate 3-monooxygenase oxygenase component; PFAM: 4-hydroxyphenylacetate 3-hydroxylase.
 
  
 0.755
Msed_0995
TIGRFAM: 3,4-dihydroxyphenylacetate 2,3-dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
 
  
 0.707
Msed_0993
PFAM: General substrate transporter; major facilitator superfamily MFS_1.
       0.636
Msed_0415
PFAM: NADH:flavin oxidoreductase/NADH oxidase.
  
  
 0.635
Msed_1776
PFAM: 4-hydroxyphenylacetate 3-hydroxylase.
 
  
 0.491
Msed_1226
TIGRFAM: cob(II)yrinic acid a,c-diamide reductase; PFAM: nitroreductase.
  
  
 0.455
Msed_0046
PFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase.
  
  
 0.432
Msed_0992
PFAM: Bacterio-opsin activator, HTH domain protein.
       0.431
Msed_0018
TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
 
   
 0.424
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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