STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Msed_1007PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR. (247 aa)    
Predicted Functional Partners:
Msed_1008
Acetyl-CoA acetyltransferase-like protein.
  
 
 0.830
Msed_1009
PFAM: protein of unknown function DUF35.
     
 0.781
mre11
Metallophosphoesterase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family.
  
 
 0.708
Msed_1903
PFAM: NADH/Ubiquinone/plastoquinone (complex I).
  
 
 0.628
Msed_1895
NADH dehydrogenase subunit A.
   
 
 0.626
Msed_0415
PFAM: NADH:flavin oxidoreductase/NADH oxidase.
 
  
 0.622
Msed_1899
TIGRFAM: NADH-quinone oxidoreductase, chain I; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein.
   
 
 0.613
Msed_1896
TIGRFAM: NADH (or F420H2) dehydrogenase, subunit C; PFAM: NADH dehydrogenase (ubiquinone), 30 kDa subunit.
  
 
 0.609
Msed_1897
PFAM: NADH-ubiquinone oxidoreductase, chain 49kDa; Belongs to the complex I 49 kDa subunit family.
  
 
 0.609
Msed_2012
TIGRFAM: NADH-quinone oxidoreductase, B subunit; PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit; Belongs to the complex I 20 kDa subunit family.
  
 
 0.595
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.