Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_1035PFAM: phosphoesterase. (451 aa)    
Predicted Functional Partners:
Msed_0633
D-fructose 1,6-bisphosphatase; PFAM: inositol monophosphatase.
    
  0.900
Msed_1034
PFAM: cobalt transport protein.
 
     0.801
Msed_1033
PFAM: ABC transporter related; SMART: AAA ATPase.
       0.773
Msed_1032
Hypothetical protein.
       0.732
Msed_0313
PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin.
  
     0.537
Msed_1305
PFAM: high-affinity nickel-transporter; Belongs to the NiCoT transporter (TC 2.A.52) family.
  
     0.495
Msed_0705
Physarolisin II, Serine peptidase, MEROPS family S53; PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin.
  
     0.448
Msed_0800
PFAM: protein of unknown function DUF929.
  
     0.427
Msed_0376
Conserved hypothetical protein.
 
     0.426
Msed_0451
PFAM: natural resistance-associated macrophage protein.
 
   
 0.400
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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