Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Msed_1053PFAM: GCN5-related N-acetyltransferase. (153 aa)    
Predicted Functional Partners:
Msed_1054
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); PFAM: malic enzyme domain protein; malic enzyme, NAD-binding.
   
   0.808
Msed_1850
TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain.
  
  
 0.505
Msed_1603
Glutamine--fructose-6-phosphate transaminase; TIGRFAM: glucosamine--fructose-6-phosphate aminotransferase, isomerizing; PFAM: glutamine amidotransferase, class-II; sugar isomerase (SIS).
  
 
 0.497
Msed_1659
PFAM: SpoVT/AbrB domain protein.
 
    0.487
Msed_0551
PFAM: SpoVT/AbrB domain protein.
 
    0.474
Msed_1968
Phosphate uptake regulator, PhoU; PFAM: SpoVT/AbrB domain protein; PhoU family protein.
 
    0.443
Msed_1055
PFAM: General substrate transporter; major facilitator superfamily MFS_1.
   
 
 0.441
Msed_1622
PFAM: SpoVT/AbrB domain protein.
 
    0.441
Msed_1835
PFAM: polysaccharide biosynthesis protein; virulence factor MVIN family protein.
 
  
 0.433
Msed_1845
TIGRFAM: glucose-1-phosphate thymidyltransferase; PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase.
  
  
 0.432
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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