STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_1074PFAM: Carotene hydroxylase. (157 aa)    
Predicted Functional Partners:
Msed_1073
TIGRFAM: Phytoene dehydrogenase-related protein; PFAM: amine oxidase; FAD dependent oxidoreductase.
 
   
 0.982
Msed_1075
PFAM: Squalene/phytoene synthase.
 
   
 0.953
Msed_1076
Hypothetical protein.
 
     0.819
Msed_1077
Hypothetical protein.
       0.661
Msed_1072
PFAM: Alpha/beta hydrolase fold-3 domain protein.
       0.592
Msed_0439
Deoxyribodipyrimidine photo-lyase type I; PFAM: DNA photolyase, FAD-binding; DNA photolyase domain protein.
  
   
 0.522
rgy
Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
      
 0.494
Msed_0635
PFAM: amine oxidase; FAD dependent oxidoreductase.
 
   
 0.405
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.