STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_1083Hypothetical protein. (183 aa)    
Predicted Functional Partners:
Msed_1294
PFAM: heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family.
    
 0.944
Msed_0640
PFAM: heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family.
  
  
 
0.908
priS
DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...]
 
    0.572
rpl10e
PFAM: ribosomal protein L10E; Belongs to the universal ribosomal protein uL16 family.
  
 
 0.572
Msed_1791
PFAM: protein of unknown function, ATP binding.
  
 
 
 0.571
Msed_1084
Hypothetical protein.
       0.565
Msed_0602
PFAM: glutamine synthetase, catalytic region.
   
 
 0.562
Msed_1612
TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region; glutamine synthetase, beta-Grasp.
   
 
 0.562
Msed_1730
PFAM: protein of unknown function DUF373.
  
     0.550
Msed_0224
PFAM: protein of unknown function DUF343.
 
     0.504
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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