STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_1118D-lactate dehydrogenase; PFAM: FAD linked oxidase domain protein. (452 aa)    
Predicted Functional Partners:
Msed_0554
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; protein of unknown function DUF224, cysteine-rich region domain protein.
 
 
 0.953
Msed_0552
PFAM: FAD linked oxidase domain protein.
 
  
 
0.932
Msed_1042
PFAM: malate synthase.
  
 
 0.925
Msed_0256
Glyoxylate reductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
   
 0.923
Msed_0553
PFAM: FAD linked oxidase domain protein.
  
  
 
0.923
Msed_0892
Transcriptional regulator, GntR family; PFAM: aminotransferase, class I and II.
    
 0.904
Msed_2120
Putative transcriptional regulator, GntR family; PFAM: aminotransferase, class I and II.
    
 0.904
Msed_0436
D-lactate dehydrogenase; PFAM: FAD linked oxidase domain protein.
  
  
 
0.903
Msed_2130
Phosphoglycolate phosphatase; Catalyzes the dephosphorylation of 2-phosphoglycolate.
    
  0.900
Msed_0295
PFAM: protein of unknown function DUF224, cysteine-rich region domain protein.
 
  
 0.884
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.