STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_1142TIGRFAM: CRISPR-associated protein Cas5 family; CRISPR-associated protein Cas5. (241 aa)    
Predicted Functional Partners:
Msed_1143
TIGRFAM: CRISPR-associated regulatory protein, Csa2 family; CRISPR-associated autoregulator DevR family; PFAM: CRISPR-associated regulatory Csa2 family protein.
  
 
 0.985
Msed_1141
TIGRFAM: CRISPR-associated helicase Cas3; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like.
  
 
 0.956
Msed_1144
TIGRFAM: CRISPR-associated protein, Csa5 family.
   
 
 0.944
Msed_1140
CRISPR-associated nuclease, Cas3 family; TIGRFAM: CRISPR-associated HD domain protein.
   
   0.928
Msed_1139
Hypothetical protein.
       0.784
Msed_1171
TIGRFAM: CRISPR-associated HD domain protein.
  
 
 0.656
Msed_1145
CRISPR-associated HTH regulatory protein, Csa3 family; TIGRFAM: CRISPR locus-related DNA-binding protein.
     
 0.602
rnp2
Ribonuclease P protein subunit Rpp14; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
      
 0.488
Msed_1163
Hypothetical protein.
  
  
 0.426
cas2
CRISPR-associated protein, Cas2 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
     
 0.423
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.