STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_1177PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase. (435 aa)    
Predicted Functional Partners:
Msed_0295
PFAM: protein of unknown function DUF224, cysteine-rich region domain protein.
 
 
 0.961
Msed_1178
PFAM: glycerophosphoryl diester phosphodiesterase.
 
 
 0.948
egsA
3-dehydroquinate synthase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
 
  
 0.937
Msed_1176
PFAM: carbon monoxide dehydrogenase subunit G.
       0.894
Msed_1509
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
 
 
 0.821
Msed_1179
PFAM: binding-protein-dependent transport systems inner membrane component.
 
   
 0.768
Msed_1180
Carbohydrate ABC transporter ATP-binding protein, CUT1 family; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; TC 3.A.1.1.-.
       0.662
Msed_1181
Carbohydrate ABC transporter substrate-binding protein, CUT1 family; PFAM: extracellular solute-binding protein, family 1; TC 3.A.1.1.-.
       0.662
Msed_1175
PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; Belongs to the TPP enzyme family.
 
  
 0.596
Msed_0947
Fe-S oxidoreductase-like protein.
 
  
 0.568
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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