Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Msed_1181Carbohydrate ABC transporter substrate-binding protein, CUT1 family; PFAM: extracellular solute-binding protein, family 1; TC 3.A.1.1.-. (490 aa)    
Predicted Functional Partners:
Msed_1179
PFAM: binding-protein-dependent transport systems inner membrane component.
 
     0.927
Msed_1180
Carbohydrate ABC transporter ATP-binding protein, CUT1 family; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; TC 3.A.1.1.-.
 
     0.802
Msed_0420
PFAM: major facilitator superfamily MFS_1.
  
     0.733
Msed_0254
PFAM: major facilitator superfamily MFS_1.
  
     0.685
Msed_1178
PFAM: glycerophosphoryl diester phosphodiesterase.
       0.671
Msed_1447
Amino acid/polyamine/organocation transporter, APC superfamily; PFAM: amino acid permease-associated region; TC 2.A.3.
  
     0.671
Msed_1156
PFAM: protein of unknown function DUF395, YeeE/YedE.
  
     0.665
Msed_1176
PFAM: carbon monoxide dehydrogenase subunit G.
       0.662
Msed_1177
PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase.
       0.662
Msed_1110
TIGRFAM: transposase, IS605 OrfB family; PFAM: transposase, IS605 OrfB.
  
     0.659
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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