STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Msed_1226TIGRFAM: cob(II)yrinic acid a,c-diamide reductase; PFAM: nitroreductase. (222 aa)    
Predicted Functional Partners:
ubiX
3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
    
  0.901
cbiA
Cobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
 0.865
Msed_0415
PFAM: NADH:flavin oxidoreductase/NADH oxidase.
  
  
 0.765
Msed_0251
PFAM: ABC-2 type transporter.
  
  
 0.732
Msed_0349
Hypothetical protein.
  
  
 0.732
Msed_0567
PFAM: ABC-2 type transporter.
  
  
 0.732
Msed_0870
PFAM: ABC-2 type transporter.
  
  
 0.732
Msed_1224
PFAM: AMP-dependent synthetase and ligase; regulatory protein, ArsR.
   
 
 0.719
Msed_0639
methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
  
  
 0.704
Msed_0995
TIGRFAM: 3,4-dihydroxyphenylacetate 2,3-dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
  
  
 0.704
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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