STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Msed_1237Methyltransferase type 11; PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11. (230 aa)    
Predicted Functional Partners:
Msed_1036
PFAM: UbiA prenyltransferase.
 
  
 0.939
Msed_0428
PFAM: NADPH-dependent FMN reductase; flavodoxin/nitric oxide synthase.
     
 0.900
Msed_1295
ABC-1 domain protein; PFAM: protein of unknown function RIO1; ABC-1 domain protein.
    
 
 0.808
Msed_1236
PFAM: beta-lactamase domain protein.
       0.668
Msed_0691
PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
 
 0.577
Msed_0322
PFAM: Rieske [2Fe-2S] domain protein.
  
  
 0.510
Msed_1191
Rieske (2Fe-2S) domain protein; A soxNL-like fusion sequence appears to have a function related to Fe(II) oxidation; PFAM: Rieske [2Fe-2S] domain protein.
  
  
 0.506
Msed_2135
Geranylgeranyl-diphosphate synthase / farnesyl-diphosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
 
 0.488
Msed_1462
Fumarase; PFAM: fumarate lyase.
  
  
 0.435
Msed_0288
PFAM: Rieske [2Fe-2S] domain protein.
   
  
 0.427
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.