STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Msed_1237Methyltransferase type 11; PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11. (230 aa)    
Predicted Functional Partners:
Msed_1036
PFAM: UbiA prenyltransferase.
 
 
 0.952
Msed_0428
PFAM: NADPH-dependent FMN reductase; flavodoxin/nitric oxide synthase.
   
 
  0.903
Msed_1295
ABC-1 domain protein; PFAM: protein of unknown function RIO1; ABC-1 domain protein.
    
 
 0.840
Msed_1236
PFAM: beta-lactamase domain protein.
       0.668
Msed_0691
PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
 
 0.547
Msed_0322
PFAM: Rieske [2Fe-2S] domain protein.
  
    0.454
Msed_2135
Geranylgeranyl-diphosphate synthase / farnesyl-diphosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
 
 0.452
Msed_1191
Rieske (2Fe-2S) domain protein; A soxNL-like fusion sequence appears to have a function related to Fe(II) oxidation; PFAM: Rieske [2Fe-2S] domain protein.
  
    0.449
Msed_1462
Fumarase; PFAM: fumarate lyase.
  
  
 0.449
Msed_2096
TIGRFAM: 4-hydroxybenzoate polyprenyltransferase, putative; PFAM: UbiA prenyltransferase.
 
  
 0.413
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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