STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Msed_1241TIGRFAM: mercuric reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (448 aa)    
Predicted Functional Partners:
Msed_1212
PFAM: Transketolase, central region; Transketolase domain protein.
 
 0.964
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).
 
 0.874
Msed_1213
Pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase, E1 component.
  
 
 0.845
Msed_1242
SMART: TRASH domain protein.
       0.779
Msed_1553
Hypothetical protein.
   
 0.734
Msed_1582
succinyl-CoA synthetase (ADP-forming) beta subunit; PFAM: ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein.
  
 0.731
Msed_0153
TIGRFAM: glutaredoxin-like domain protein.
   
 0.729
Msed_0776
TIGRFAM: thioredoxin; PFAM: Thioredoxin domain.
   
 0.729
Msed_1614
TIGRFAM: thioredoxin; PFAM: Redoxin domain protein; Thioredoxin domain.
   
 0.729
Msed_0455
PFAM: Lactate/malate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.699
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.